Workshop on Quantitative Systems Biotechnology

This workshop was held at the National Science Foundation (NSF) on September 13 and 14. This document was sponsored by NSF of the U.S. government under NSF Award No. BES-0004066, awarded to the International Technology Research Institute (ITRI, Inc.). The government has certain rights to this material. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the United States government, the authors' parent institutions, or ITRI, Inc.

Workshop Report


The objective for future engineering research is to augment the process of predicting the phenotypic behavior of a living organism from the genomic information being generated for that organism and the well defined environmental conditions that cause the expression of that genome. This would include the prediction of emergent properties of complex combinations of genes as well as the further elucidation of metabolic pathways and the alteration and regulation of these pathways for well defined goals.

There are three questions we would like to cover at the workshop in order to provide a more focused basis for a NSF research initiative:

  1. What are the unmet (near term) opportunities and needs associated with using genomic information for phenotype prediction?
  2. What are the developments needed in test-bed and high throughput screening systems?
  3. What new mathematical tools, or those that can be adopted from other disciplines, are needed to use genomic information for predictive purposes?

Workshop Agenda

September 13, 2000--Room 110

September 14, 2000--Room 580

Invited Experts

Reference Information